Step-Up Trial

This therapy is based on thermal ablation of damaged lung with steam vapour. This in turn leads to an inflammatory reaction and fibrosis in a portion of the lung inducing lung volume reduction. Patients will be treated with the InterVapor System in 1 to 2 segments in the upper lobes of each lung (2 to 3 segments total). Patients will also receive Optimal Medical Therapy. Recruitment to open at the Royal Brompton Hospital in the near future.