BREATHE : Airway Scaffolds for Emphysema-related Hyperinflation: Six-Month Results from the BREATHE Trial
This pooled first-in-human analysis evaluated a novel bronchoscopic airway scaffold designed to reduce hyperinflation in emphysema by enabling trapped air to escape. The treatment was technically feasible and showed meaningful improvements in lung function, symptoms, and quality of life, with an acceptable safety profile despite some procedure-related adverse events.
Tana A, Valipour A, Ing A, Steinfort DP, Orton CM, Klooster K, Klemm T, Williamson JP, Christie JJ, Garner JL, Koster TD. Airway scaffolds for emphysema-related hyperinflation: six-month results from the BREATHE trial. American Journal of Respiratory and Critical Care Medicine. 2025 Jul;211(7):1175-84.